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Advantages, Disadvantages and applications of Paper chromatography

Advantages:

1. Simplicity:

  • Paper chromatography requires minimal equipment and is easy to set up.

2. Low Cost:

  • Relatively inexpensive compared to techniques like HPLC or GC.

3. Versatility:

  • Can be used to separate a variety of polar and non-polar compounds.

4. Qualitative and Semi-quantitative Analysis:

  • Useful for identification and comparative analysis.

Here's the diagram illustrating the "Advantages of Paper Chromatography
Here's the diagram illustrating the "Advantages of Paper Chromatography

Disadvantages:

1. Resolution:

  • Limited resolution compared to more advanced chromatographic techniques.

2. Sensitivity:

  • Not as sensitive as techniques like HPLC or GC; might miss trace components.

3. Quantification:

  • Quantitative analysis is less precise compared to other methods.

4. One-time Use:

  • Each paper can only be used once.

 "Disadvantages of Paper Chromatography"
Disadvantages of Paper Chromatography

Applications:

1. Education:

  • Commonly used in teaching labs because of its simplicity and visualization capabilities.

2. Food Industry:

  • Used to detect and separate food additives, colors, and flavors.

3. Pharmaceuticals:

  • Identification and separation of drug components.

4. Biochemistry:

  • Separation of amino acids, nucleotides, and other biomolecules.

5. Forensics:

  • Used for certain types of forensic analysis, such as ink analysis in questioned document examinations.

 "Applications of Paper Chromatography"
Flowchart of "Applications of Paper Chromatography"


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