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Advantages & Disadvantages of HPLC

S-7-INSTRUMENTAL METHODS OF ANALYSIS
1 min read

Advantages of HPLC

  1. High Resolution: Effective separation of complex mixtures.

  2. Versatility: Applicable to a wide range of compounds.

  3. Precision: Reliable quantitative analysis.

  4. Speed: Faster than traditional methods, especially with UHPLC.

Disadvantages of HPLC

  1. Cost: High initial investment and maintenance.

  2. Maintenance: Regular upkeep and column replacement needed.

  3. Skill Requirement: Requires trained operators for optimal use.

  4. Solvent Consumption: High solvent use can be costly and environmentally impactful.


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