Advantages of Targeted Drug Delivery:
1. Improved Efficacy:
Targeted systems can increase the amount of drug reaching the desired site, potentially enhancing its therapeutic effects.
2. Reduced Side Effects:
By sparing non-target tissues from drug exposure, side effects can be minimized.
3. Decreased Dosage Frequency:
With more drug reaching the target site and staying there for extended periods, it may be possible to reduce the frequency of administration.
4. Enhanced Patient Compliance:
Reduced side effects and decreased dosage frequency can improve patient compliance.
5. Drug Protection:
Some targeted delivery systems can protect drugs from degradation in the bloodstream or from premature release.
Disadvantages of Targeted Drug Delivery:
1. Complexity and Cost:
Development and manufacturing of targeted delivery systems can be complex and costly.
2. Potential Toxicity:
Some materials used in targeted systems might evoke an immune response or other adverse reactions.
3. Limited to Certain Drugs:
Not all drugs or conditions are amenable to targeted delivery.
4. Release Control:
Ensuring controlled and sustained release at the target site can be challenging.
5. Regulatory Challenges:
Due to their complexity, targeted delivery systems may face rigorous regulatory scrutiny.
