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Hyperlipidemia

  • Hyperlipidemia refers to elevated levels of lipids (fats) in the blood, including cholesterol and triglycerides.

  • It is a significant risk factor for the development of cardiovascular diseases.

Types of Lipids Involved:

  1. Low-Density Lipoprotein (LDL) Cholesterol: Often termed "bad" cholesterol; high levels can lead to plaque buildup in arteries.

  2. High-Density Lipoprotein (HDL) Cholesterol: Known as "good" cholesterol; helps remove LDL cholesterol from the bloodstream.

  3. Triglycerides: Elevated levels can contribute to atherosclerosis and pancreatitis.

Causes:

  • Genetic Factors: Familial hypercholesterolemia.

  • Diet: High intake of saturated fats, trans fats, and cholesterol.

  • Lifestyle: Sedentary behavior, obesity, and excessive alcohol consumption.

  • Medical Conditions: Diabetes, hypothyroidism, and kidney disease.

Symptoms:

  • Often asymptomatic; typically detected through blood tests.

  • In severe cases, can lead to symptoms of cardiovascular diseases like chest pain or stroke.

Complications:

  • Atherosclerosis: Hardening and narrowing of arteries.

  • Cardiovascular Diseases: Increased risk of heart attacks, strokes, and peripheral artery disease.

Management:

  • Lifestyle Modifications: Healthy diet, regular exercise, weight management, and smoking cessation.

  • Medications: Statins, fibrates, bile acid sequestrants, and other lipid-lowering agents


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