Hyper means “high” and lipidemia means “level of lipids”.
ANTI – HYPERLIPIDEMIC AGENTS are those drugs which is used in the treatment of hyperlipidemia.
Any abnormally increased lipid (fats, cholesterol, or triglycerides) or lipoprotein levels in the blood are known as hyperlipidemia.
Hyperlipidemia cause atherosclerotic which further cause heart attack, stroke, and many other heart diseases.
Heart attack, stroke, and other types of heart disease are all caused by atherosclerotic plaque, which is caused by hyperlipidemia.
LIPIDS-
These are important for our body.
These are present in three forms in the body.
a. Cholesterol
b. Triglycerides
c. Phospholipids
These lipids are insoluble in blood plasma, so they must be transported throughout the body in the form of protein complex which is known as lipoproteins.
These lipoproteins further divide-
a. Chylomicron
Made in the digestive tracts from dietary lipids.
It has triglycerides and small amount of cholesterol in it.
b. Very low-density lipoproteins (VLDL)
The liver in which these lipoproteins are made.
It has a minor quantity of cholesterol and triglycerides in it.
c. Low density lipoproteins (LDL)
It is also known as "bad cholesterol,"
It has high amount of cholesterol in it.
As LDL levels increase, plaque accumulates in the blood vessels, causing additional cardiac issues.
d. High density lipoproteins (HDL)
It is also known as "healthy cholesterol."
It is Produces in liver and in small intestine
It has phospholipids, cholesterol, and proteins in it.
It works by preventing the accumulation of cholesterol in the arteries.
When Low density lipoprotein (LDL) cholesterol levels rise, which causes hyperlipidemia because excess LDL builds up in the innermost layer of the artery and results in the development of plaque that can cause heart problems.
Due to this reason, Low density lipoproteins (LDL) are known as bad cholesterol.
This extra cholesterol is eliminated by high density lipoproteins, so it known as good cholesterol.
