Anti-Protozoal Agents

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• Anti-protozoal agents are medications designed to eliminate protozoan parasites by disrupting their essential life processes, including:

  • Cell membrane integrity

  • Protein synthesis

  • DNA replication

  • Energy metabolism

• These agents are infection-specific, meaning their use depends on the type of protozoan infection and disease severity.

Classification of Anti-Protozoal Agents

1) Amoebicidal Agents

• Used for amoebiasis and other protozoal infections

  • Metronidazole

  • Tinidazole

  • Ornidazole

  • Diloxanide

  • Iodoquinol

2) Antimalarial Agents

• Used for malaria caused by Plasmodium species

  • Atovaquone

3) Anti-Leishmaniasis & Trypanosomiasis Agents

• Pentamidine Isethionate

  • Eflornithine

Selection of Anti-Protozoal Agents

• Based on infection type, severity, and patient health condition.

• Some agents have broad-spectrum activity, while others are specific to certain protozoan species.

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