Definition
Antitoxins are purified antibodies against bacterial toxins, used for immediate immunity in toxin-related infections.
General Method of Preparation
1) Hyperimmunization of Animals (usually horses)
Horses are injected with small, increasing doses of bacterial toxin/toxoid.
2) Collection of Antibody-Rich Plasma
Blood is drawn after sufficient antibody production.
3) Purification of Antibodies
Plasma is purified using precipitation, chromatography, or filtration techniques.
4) Sterile Packaging and Storage
Stored at 2–8°C, sometimes freeze-dried for stability.
Examples of Antitoxins
Diphtheria Antitoxin
Tetanus Antitoxin
