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Applications of Ion Exchange Chromatography

Protein Purification:

  • Isolation and purification of proteins, enzymes, and antibodies.

  • Separation based on the isoelectric point (pI) of proteins.

Nucleic Acid Purification:

  • Separation and purification of DNA, RNA, and oligonucleotides.

  • Removal of nucleotides and other charged contaminants.

Water Treatment:

  • Removal of metal ions and deionization of water for industrial and laboratory use.

Pharmaceutical Industry:

  • Purification of drugs and active pharmaceutical ingredients (APIs).

  • Analysis of charged drug impurities.

Food and Beverage Industry:

  • Purification of amino acids, vitamins, and other bioactive compounds.

  • Removal of bitter compounds or off-flavors.

Environmental Analysis:

  • Detection and quantification of ions in water and soil samples.

  • Removal of heavy metals from wastewater.

Clinical and Diagnostic Applications:

  • Purification of biomarkers for diagnostic assays.

  • Fractionation of blood plasma proteins.

Biotechnology:

  • Purification of recombinant proteins and other biologics.

  • Analysis and separation of metabolites and charged intermediates.


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