Structure
Astemizole is a non-sedating second-generation antihistamine with a benzoxazole ring fused to a piperazine moiety.
Chemical Formula: C₂₇H₃₁NO₃
Mode of Action
Selective H₁-receptor antagonist with minimal penetration of the blood-brain barrier, reducing sedation.
It also exhibits anti-inflammatory properties.
Uses of Astemizole
Allergic Rhinitis: Relieves symptoms like sneezing, itching, and runny nose.
Urticaria: Alleviates hives and skin itching.
Chronic Idiopathic Urticaria: Effective in long-term management of hives.