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Azatadine maleate

Structure (Azatadine maleate)

  • Azatadine maleate is a first-generation antihistamine with a tricyclic structure fused to a pyridine ring.

  • It forms a salt with maleic acid to improve solubility.

  • Chemical Formula: C₁₉H₂₇N₃·C₄H₄O₄

Mode of Action

  • Acts as an H₁-receptor antagonist with anticholinergic and sedative effects.

  • It inhibits histamine-mediated allergic responses.

Uses

  • Allergic Reactions: Treats symptoms such as sneezing, itching, and runny nose.

  • Urticaria: Alleviates hives and skin itching.

  • Cold Symptoms: Helps reduce nasal congestion and other related discomforts.


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