Azatadine maleate

Structure (Azatadine maleate)

• Azatadine maleate is a first-generation antihistamine with a tricyclic structure fused to a pyridine ring.

• It forms a salt with maleic acid to improve solubility.

• Chemical Formula: C₁₉H₂₇N₃·C₄H₄O₄

Structure Azatadine maleate

Mode of Action

• Acts as an H₁-receptor antagonist with anticholinergic and sedative effects.

• It inhibits histamine-mediated allergic responses.

Uses

• Allergic Reactions: Treats symptoms such as sneezing, itching, and runny nose.

• Urticaria: Alleviates hives and skin itching.

• Cold Symptoms: Helps reduce nasal congestion and other related discomforts.