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Bepridil Hydrochloride

Structure of Bepridil Hydrochloride

  • Bepridil hydrochloride is a benzothiazepine derivative with a phenyl ring attached to a thiazepine ring containing multiple substituents.

  • Chemical Formula: C₂₅H₃₈ClN₃OS

Structure of Bepridil Hydrochloride
Structure of Bepridil Hydrochloride

Mode of Action

  • Calcium Channel Blocking: Inhibits L-type calcium channels in cardiac and vascular smooth muscle.

  • Vasodilation: Causes relaxation of vascular smooth muscle, reducing blood pressure.

  • Antiarrhythmic Effects: Prolongs refractory periods and suppresses abnormal heart rhythms.

  • Other Effects: Exhibits anti-anginal and antiarrhythmic properties.

Uses

  1. Hypertension: Lowers blood pressure through vasodilation.

  2. Angina Pectoris: Reduces myocardial oxygen demand and alleviates chest pain.

  3. Arrhythmias: Manages various cardiac arrhythmias.

  4. Coronary Artery Disease: Improves coronary blood flow.


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