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Physicochemical parameter used in quantitative structure activity relationship:Partition coefficient
Taft’s steric parameter & Hansch analysis
Hammett Electronic parameters
Various approaches used in drug design.
Introduction to Drug Design: Types of Drug Design
Dapsone (4,4'-diaminodiphenyl sulfone): Chemical Structure, Mechanism, SAR, Synthesis, Uses, effect
Cotrimoxazole (Sulfamethoxazole + Trimethoprim): Chemical Structure, Mechanism, Uses, Side effects
Trimethoprim: Chemical Structure, Mechanism of Action, SAR, Synthesis, Uses & Side effects
Folate reductase inhibitors
Sulfasalazine: Chemical Structure, Mechanism of Action & Uses