Structure
Buclizine hydrochloride contains a piperazine ring bonded to a diphenylmethyl group with an ethyl substituent. The hydrochloride salt improves solubility.
Chemical Formula: C₂₁H₂₈ClN₃·HCl
Mode of Action
Acts as an H₁-receptor antagonist with anticholinergic and antiemetic properties.
It reduces histamine-induced symptoms and prevents nausea.
Uses of Buclizine hydrochloride
Motion Sickness: Prevents and treats nausea and vomiting related to travel.
Vertigo: Provides relief from dizziness associated with vestibular disorders.