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Buclizine hydrochloride

Structure (Buclizine hydrochloride)

Buclizine hydrochloride contains a piperazine ring bonded to a diphenylmethyl group with an ethyl substituent. The hydrochloride salt improves solubility.
Chemical Formula: C₂₁H₂₈ClN₃·HCl

Structure Buclizine hydrochloride

Mode of Action

Acts as an H₁-receptor antagonist with anticholinergic and antiemetic properties.
It reduces histamine-induced symptoms and prevents nausea.

Uses

Motion Sickness: Prevents and treats nausea and vomiting related to travel.
Vertigo: Provides relief from dizziness associated with vestibular disorders.

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