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Busulfan

Structure

  • Busulfan Chemical Structure – C6H14O6S2

Busulfan

Mode of action

  • The It is a bifunctional alkylating agent.

  • It interacts with the thiol group of the protein and nucleic acid and forms DNA-Protein and DNA-DNA cross linkage

  • And these cross-linkages inhibit the synthesis and function of DNA.

Uses

  • It recommended as a treatment for chronic myelogenous leukaemia.



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