Butamben

Structure

• Butamben is an amino benzoic acid derivative with a butyl ester group attached to the benzene ring, providing enhanced anesthetic properties.

• Chemical Formula: C₁₀H₁₉NO₂

  

Structure of Butamben

Mode of Action

• Sodium Channel Blockade: Blocks nerve impulse transmission by inhibiting voltage-gated sodium channels.

• Membrane Permeabilization: Stabilizes nerve membranes, reducing excitability.

Uses

• Topical Anesthesia: Applied to mucous membranes and skin for numbing before minor procedures.

• Ophthalmic Anesthesia: Used in eye surgeries for corneal numbing.

• Dental Preparations: Incorporated in gels and creams for dental applications.

Side Effects

• Local Irritation: Redness and mild irritation at the application site.

• Allergic Reactions: Rare but possible in sensitive individuals.