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Butamben

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Structure

  • Butamben is an amino benzoic acid derivative with a butyl ester group attached to the benzene ring, providing enhanced anesthetic properties.

  • Chemical Formula: C₁₀H₁₉NO₂

    formula of Butamben
Structure of Butamben
Structure of Butamben

Mode of Action

  • Sodium Channel Blockade: Blocks nerve impulse transmission by inhibiting voltage-gated sodium channels.

  • Membrane Permeabilization: Stabilizes nerve membranes, reducing excitability.

Uses

  • Topical Anesthesia: Applied to mucous membranes and skin for numbing before minor procedures.

  • Ophthalmic Anesthesia: Used in eye surgeries for corneal numbing.

  • Dental Preparations: Incorporated in gels and creams for dental applications.

Side Effects

  • Local Irritation: Redness and mild irritation at the application site.

  • Allergic Reactions: Rare but possible in sensitive individuals.


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