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Cetirizine

BP-S-5-MEDICINAL CHEMISTRY
1 min read

Structure of Cetirizine

  • Cetirizine is a metabolite of hydroxyzine with a piperazine ring substituted with a carboxylic acid group and an aromatic ring.

Chemical Formula: C₂₂H₂₁ClN₂O₃

Structure of Cetirizine
Structure of Cetirizine

Mode of Action

  • Selective peripheral H₁-receptor antagonist with minimal CNS penetration.

  • It effectively reduces histamine-induced symptoms with reduced sedation.

Uses

  • Allergic Rhinitis: Effective in treating symptoms like sneezing, itching, and runny nose.

  • Chronic Urticaria: Alleviates hives and skin itching.

  • Seasonal Allergies: Provides relief from pollen-induced allergic symptoms.


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