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Chlorcyclizine hydrochloride

Structure (Chlorcyclizine hydrochloride)

  • Chlorcyclizine hydrochloride is a diphenylmethylpiperazine derivative with a chlorinated aromatic ring.

  • The hydrochloride salt improves solubility.

  • Chemical Formula: C₁₆H₂₈ClN₃·HCl

Mode of Action

Acts as an H₁-receptor antagonist with additional anticholinergic and sedative properties.

It inhibits histamine-mediated responses.

Uses

Allergic Reactions: Treats symptoms like sneezing, itching, and runny nose.

Motion Sickness: Prevents and alleviates nausea and vomiting associated with travel.


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