Structure (Chlorpheniramine maleate)
Chlorpheniramine maleate is a first-generation antihistamine with a dibenzyl structure connected to an ethylamine chain.
It forms a salt with maleic acid to enhance solubility.
Chemical Formula: C₁₇H₂₈ClN₃·C₄H₄O₄
Mode of Action
Blocks H₁-receptors both peripherally and centrally, reducing allergic symptoms.
Exhibits anticholinergic and sedative effects.
Uses
Allergic Rhinitis: Relieves symptoms such as sneezing, itching, and runny nose.
Urticaria: Alleviates hives and skin itching.
Cold Symptoms: Helps reduce nasal congestion and other cold-related symptoms.