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Chlorpromazine Hydrochloride: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Structure:

  • C17H19ClN2S.HCl

Mechanism of Action:

  • Chlorpromazine blocks dopamine receptors (D1 and D2) in the brain which decreases psychotic thinking and behavior.

Uses:

  • It's used to treat various types of mental/mood disorders including schizophrenia, psychotic disorders, manic phase of bipolar disorder, and severe behavioral problems in children.

Side Effects:

  • It can cause drowsiness, dizziness, dry mouth, blurred vision, constipation, and weight gain. More serious side effects include severe restlessness/constant need to move (akathisia), shaking (tremor), and muscle stiffness.

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