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Delavirdine: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Formula:

  • C22H28N6O3S

Structure of Delavirdine
Structure of Delavirdine

Mechanism of Action:

  • Delavirdine is an NNRTI that works against HIV.

  • Similar to loviride, delavirdine binds to a distinct site on the reverse transcriptase enzyme, inhibiting the enzyme's activity and preventing viral replication.

Uses:

  • Delavirdine is used in combination with other antiretroviral drugs to treat HIV infection.

Side Effects:

Some common side effects of delavirdine include:

  • Rash

  • Fatigue

  • Headache

  • Nausea

  • Diarrhea

  • Serious side effects may include:

  • Severe skin reactions (e.g., Stevens-Johnson syndrome)

  • Hepatotoxicity


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