Structure
Digitoxin Chemical Structure – C41H64O13
Mode of action
As a result of digitoxin's inhibition of the Na-K-ATPase membrane pump, intracellular calcium and sodium concentrations rise.
Calcium concentrations that are higher inside of cells may encourage contractile protein activation (e.g., actin, myosin).
Uses
It is used to treat irregular cardiac rhythms and heart failure.
It improves heart performance and helps to maintaining heart rate management.