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Digitoxin

Structure

  • Digitoxin Chemical Structure – C41H64O13

Digitoxin

Mode of action

  • As a result of digitoxin's inhibition of the Na-K-ATPase membrane pump, intracellular calcium and sodium concentrations rise.

  • Calcium concentrations that are higher inside of cells may encourage contractile protein activation (e.g., actin, myosin).

Uses

  • It is used to treat irregular cardiac rhythms and heart failure.

  • It improves heart performance and helps to maintaining heart rate management.


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