Structure
Digoxin Chemical Structure – C41H64O14
Mode of action
As a result of digitoxin's inhibition of the Na-K-ATPase membrane pump, intracellular calcium and sodium concentrations rise.
Calcium concentrations that are higher inside of cells may encourage contractile protein activation (e.g., actin, myosin).
Uses
Digoxin is a cardiac glycoside used to modulate the ventricular response rate in chronic atrial fibrillation and to treat mild to moderate heart failure.
It improves heart performance and helps to maintaining heart rate management.