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Dihydroergotamine: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Structure/Formula:

  • C33H37N5O5

Structure of Dihydroergotamine
Structure of Dihydroergotamine

Mechanism of Action:

  • Dihydroergotamine is an ergot alkaloid that works as a serotonin receptor agonist. It also has alpha-adrenergic antagonist properties and affects the vascular smooth muscle.

Uses:

  • It is primarily used for the treatment of migraines. It helps alleviate headache by narrowing blood vessels in the brain.

Side Effects:

  • Side effects can include nausea, vomiting, muscle pain, dizziness, and temporary chest tightness. It may also cause rare but serious effects on the heart and blood vessels.

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