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Dimenhydrinate

Structure

  • Dimenhydrinate Molecular formula - C24H28ClN5O3

It’s a combination of Diphenhydramine and 8-chlorotheophylline.

Mode of action

  • Dimenhydrinate is a salt of Diphenhydramine and 8-Chlorotheophylline.

  • Dimenhydrinate acts centrally on the chemoreceptor trigger zone to produce an antiemetic effect. It increases the activity of the vomiting centre while reducing the sensitivity of the Labyrinth apparatus.

Synthesis

Uses

  • Dimenhydrinate is used to prevent and treat motion sickness-related nausea, vomiting, and dizziness.

  • Help in the treatment of ear congestion.


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