Chemical Structure/Formula:
C18H23NO3
Mechanism of Action:
Dobutamine primarily stimulates beta-1 adrenergic receptors in the heart, leading to increased cardiac output without significantly increasing heart rates.
It enhances myocardial contractility and stroke volume, which can be particularly beneficial in patients with heart failure or cardiogenic shock.
It also has mild beta-2 and alpha-1 agonist effects, which can lead to mild vasodilation.
Uses:
It is commonly used in the treatment of acute heart failure and in certain diagnostic heart tests (stress echocardiography).
Dobutamine can improve blood flow in individuals with poor cardiac output, helping to maintain adequate organ perfusion.
Side Effects:
The main side effects include increased heart rate, blood pressure fluctuations, and potential arrhythmias. Other effects may include anxiety, headache, nausea, and palpitations.