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Doxycycline

Chemical Structure / Formula of Doxycycline

  • Formula: C22H24N2O8

  • A semi-synthetic tetracycline with better absorption and longer half-life.


Chemical Structure of Doxycycline
Chemical Structure of Doxycycline

Mechanism of Action

  • Binds to the 30S ribosomal subunit, preventing bacterial protein synthesis.

Uses

  • First-line for Lyme disease, Rocky Mountain spotted fever, Chlamydia, and Mycoplasma pneumoniae infections.

  • Used for malaria prophylaxis and bioterrorism-related infections (anthrax, plague, tularemia).

Side Effects

  • Similar to tetracycline (GI distress, photosensitivity, tooth discoloration).

  • Esophagitis (should be taken with plenty of water).


 
 
 

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