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Electrophilic addition: an overview

  • Electrophilic addition is a fundamental chemical reaction where an electrophile and a nucleophile, typically an alkene or alkyne, combine to form a single bond.

  • This process involves the conversion of a π bond into new σ bonds, playing a crucial role in the transformation of alkenes and alkynes into more complex organic compounds.

Key Concepts of Electrophilic Addition:

1. Electrophiles and Nucleophiles:

  • Electrophiles are electron-deficient species that seek electrons.

  • Nucleophiles are electron-rich species ready to donate electrons.

  • Alkenes and alkynes act as nucleophiles due to their electron-rich π bonds.

2. Mechanism:

The reaction proceeds in two main steps:

  • Step 1: Electrophilic Attack: The electrophile attacks the electron-rich π bond, forming a carbocation intermediate.

  • Step 2: Nucleophilic Attack: The nucleophile then attacks the carbocation, forming a new σ bond.

Example: Addition of HBr to Ethene

Step 1 - Electrophilic Attack:

  • HBr's proton (H⁺) acts as the electrophile, attacking the ethene's π bond, forming a carbocation and a bromide ion (Br⁻).

H₂C=CH₂ + HBr → H₂C-CH₂⁺ + Br⁻

Step 2 - Nucleophilic Attack:

  • The bromide ion (Br⁻) then attacks the carbocation, forming bromoethane.

H₂C-CH₂⁺ + Br⁻ → H₂C-CH₂Br

Significance:

  • Electrophilic addition is vital in organic synthesis, allowing for the introduction of functional groups into alkenes and alkynes.

  • This versatility makes it indispensable in creating a myriad of organic compounds, including polymers, pharmaceuticals, and agrochemicals.

  • By employing different electrophiles, such as hydrogen halides (HX), halogens (X₂), and water (H₂O), chemists can synthesize a diverse range of functionalized molecules through this reaction mechanism.


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