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Enoxacin

Chemical Structure / Formula of Enoxacin

  • Formula: C15H17FN4O3

  • Structure: A fluorinated 4-quinolone with enhanced DNA gyrase inhibition.

Chemical Structure of Enoxacin

Mechanism of Action

  • Inhibits bacterial DNA gyrase and topoisomerase IV, leading to double-strand DNA breaks.

Uses

  • Treats UTIs, gonorrhea, prostatitis.

  • Less commonly used due to the availability of newer fluoroquinolones.

Side Effects

  • GI upset, dizziness, skin rash.

  • CNS toxicity (seizures, tremors) in patients taking NSAIDs.

  • Tendonitis, QT prolongation.


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