Enzyme kinetics is the study of the rates of enzyme-catalyzed reactions.
One of the most fundamental models in enzyme kinetics is the Michaelis-Menten model, which describes how the reaction rate depends on the concentration of substrate and the enzyme's affinity for the substrate.
Michaelis-Menten Equation
The Michaelis-Menten equation is given by:
here:
𝑣 is the initial reaction velocity.
𝑉max is the maximum reaction velocity.
[𝑆] is the substrate concentration.
𝐾𝑚 is the Michaelis constant, representing the substrate concentration at which the reaction velocity is half of 𝑉max.
Example Plot
Here's an example of how a Michaelis-Menten plot looks:
Hyperbolic Curve: Shows the relationship between [𝑆] and 𝑣.
Key Points:
At low [𝑆], 𝑣 increases linearly.
At high [𝑆], 𝑣 plateaus at 𝑉max.
