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Epithelial tissue

  • Epithelial tissues cover body surfaces, line cavities and form glands.

  • They function in protection, secretion, absorption, and transportation.

Epithelial tissues are classified based on the number of cell layers and cell shape:

Epithelial Tissues Classification

1. Simple Epithelium:

  • Single layers of cells primarily functions in absorption, secretion, and filtration.

Types:

  1. Simple Squamous Epithelium:

    • Structure: Single layer of flat cells.

    • Location: Alveoli of lungs, glomeruli of kidneys, lining of blood vessels (endothelium), and lining of body cavities (mesothelium).

    • Function: Allows for rapid diffusion and filtration.

  2. Simple Cuboidal Epithelium:

    • Structure: Single layer of cube-shaped cells.

    • Location: Kidney tubules, ducts of small glands, ovary surface.

    • Function: Secretion and absorption.

  3. Simple Columnar Epithelium:

    • Structure: Single layer of tall, column-shaped cells.

    • Location: Lining of the gastrointestinal tract, gallbladder, and some ducts of glands.

    • Function: Absorption and secretion; may have microvilli for increased surface area or cilia for movement of substances

2. Stratified Epithelium:

  • Multiple layers of cells, primarily functions in protection against abrasion.

Types:

  1. Stratified Squamous Epithelium:

    • Structure: Multiple layers with flat apical cells.

    • Location:

      • Keratinized: Epidermis of the skin.

      • Non-keratinized: Lining of the mouth, esophagus, and vagina.

    • Function: Protects underlying tissues from abrasion and pathogens.

  2. Stratified Cuboidal Epithelium:

    • Structure: Typically, two layers of cube-shaped cells.

    • Location: Ducts of sweat glands, mammary glands, and salivary glands.

    • Function: Protection and limited secretion/absorption.

  3. Stratified Columnar Epithelium:

    • Structure: Multiple layers with columnar apical cells.

    • Location: Rare; found in the male urethra and large ducts of some glands.

    • Function: Protection and secretion.

Structure of Epithelial cells

Structure:

  • Epithelial cells are closely packed together with little extracellular matrix, and they form a continuous sheet held together by cell junctions such as tight junctions, gap junctions, and desmosomes.

  • They have an apical surface facing the body cavity or external environment and a basal surface attached to the underlying connective tissue via a basement membrane.

Location:

  1. Surface epithelium: External body surfaces (skin), internal cavities (mouth, respiratory tract, and gastrointestinal tract)

  2. Glandular epithelium: Forms glands (e.g., sweat glands, salivary glands, thyroid gland)

Functions:

  1. Protection: Epithelial tissues protect the body from mechanical injury, harmful substances, and pathogens.

  2. Secretion: Glandular epithelium secretes substances like hormones, enzymes, and mucus.

  3. Absorption: Simple columnar and simple cuboidal epithelia help absorb nutrients in the gastrointestinal tract and kidney tubules.

  4. Transportation: Ciliated epithelial cells help transport particles and mucus across their surfaces.


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