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Ethambutol: Chemical Structure, Mechanism of Action, Uses & Side effects

Chemical formula:

  • C10H24N2O2

Structure of Ethambutol
Structure of Ethambutol

Mechanism of action:

  • Ethambutol inhibits the synthesis of arabinogalactan, a key component of the mycobacterial cell wall, by targeting the enzyme arabinosyltransferase, thereby inhibiting the growth of Mycobacterium tuberculosis.

Uses:

  • Ethambutol is used in combination with other antitubercular drugs for the treatment of tuberculosis (TB).

Side effects:

  • Side effects can include optic neuritis (visual disturbances and color vision impairment), peripheral neuropathy, hypersensitivity reactions, and gastrointestinal disturbances.


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