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Etidocaine

Structure

  • Etidocaine is an amide-type local anesthetic with an extended diethylaminoethyl side chain, providing prolonged anesthetic effects.

  • Chemical Formula: C₁₅H₂₈N₂O

    Formula of Etidocaine
Structure of Etidocaine
Structure of Etidocaine

Mode of Action

  • Sodium Channel Inhibition: Blocks voltage-gated sodium channels, preventing nerve impulse propagation.

  • Membrane Stabilization: Reduces nerve excitability by enhancing membrane stability.

Uses

  • Local Anesthesia: Used in dental procedures, minor surgeries, and obstetric anesthesia for prolonged numbness.

  • Topical Preparations: Applied to skin and mucous membranes for extended local pain relief.

  • Infiltration Anesthesia: Injected to provide sustained localized anesthesia during medical procedures.

Side Effects

  • Local Reactions: Redness, swelling, or irritation at the injection site.

  • Systemic Toxicity: Potential CNS excitation (e.g., seizures) and cardiovascular effects (e.g., arrhythmias) with excessive doses.


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