Eye lotions are sterile aqueous solutions used to wash or irrigate the eyes.
They help remove debris, chemicals, or other foreign materials.
Components of Eye Lotions:
Active Ingredient: Similar to ointments, can include both hydrophilic and lipophilic drugs.
Emollients and Lubricants: To provide moisturizing effects.
Thickeners: To achieve desired viscosity without being too thick.
Preservatives: If intended for multi-dose use.
Formulation Considerations:
Consistency: Must be smooth and spreadable without being too thick.
Retention and Comfort: Longer contact time than drops but less greasy than ointments.
Compatibility: Ensuring that the formulation does not interfere with vision or cause irritation.
Advantages:
Enhanced Comfort: Less greasy than ointments, leading to better patient compliance.
Moderate Retention Time: Offers a balance between prolonged contact and ease of use.
Examples:
Antiallergic Lotions: Combines antihistamines with lubricants.
Moisturizing Lotions: For dry eye treatment.
Method of Preparation:
Solution Preparation: Dissolve ingredients in sterile water.
Filtration: Filter through a sterilizing filter (0.22 µm).
Packaging: Filled into single-use or multi-dose containers under aseptic conditions.