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Factors affecting fluorescence

Fluorescence is the emission of light by a substance that has absorbed light. Several factors can influence the intensity, duration, and efficiency of fluorescence.

Here are the primary factors affecting fluorescence:

1. Nature of the Molecule:

  • Not all molecules fluoresce. The molecular structure, including the presence of conjugated systems, plays a role in determining if a molecule is fluorescent.

2. Excitation Wavelength:

  • The intensity of fluorescence can depend on the wavelength of the exciting light.

  • Each molecule has an optimal excitation wavelength that produces the maximum fluorescence emission.

3. Quantum Yield:

  • Refers to the efficiency of the fluorescence process.

  • It's the ratio of the number of photons emitted to the number of photons absorbed.

4. Environmental Factors:

  • pH: The acidity or basicity of the environment can affect the protonation state of the molecule, influencing its fluorescence.

  • Temperature: Higher temperatures generally reduce fluorescence due to increased non-radiative processes.

  • Viscosity: In more viscous environments, molecular rotation and vibration might be restricted, which can influence fluorescence.

  • Solvent: The polarity and nature of the solvent can affect fluorescence. Some solvents can enhance while others can quench fluorescence.

5. Concentration:

  • At high concentrations, self-quenching can occur where molecules absorb the emitted fluorescence of neighboring molecules.

6. Presence of Quenchers:

  • Some molecules can reduce or quench fluorescence when present. Oxygen is a common quencher.

7. Lifetime of the Excited State:

  • The longer the excited state lasts, the higher the chance for non-radiative processes to de-excite the molecule, reducing fluorescence.

8. Intersystem Crossing:

  • This is the process where the molecule moves from a singlet excited state to a triplet state.

  • Since fluorescence occurs from the singlet state, intersystem crossing to the triplet state reduces the yield of fluorescence.



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