Structure of Felodipine
Felodipine is a dihydropyridine calcium channel blocker with a substituted phenyl ring and a methoxyethyl side chain attached to the dihydropyridine core.
Chemical Formula: C₂₂H₂₄N₂O₅
Mode of Action
Calcium Channel Blocking: Selectively inhibits L-type calcium channels in vascular smooth muscle.
Vasodilation: Promotes peripheral arterial relaxation, lowering blood pressure.
Reduced Cardiac Effects: Minimal impact on heart rate and contractility.
Uses
Hypertension: Lowers blood pressure by causing vasodilation.
Angina Pectoris: Relieves chest pain by reducing myocardial oxygen demand.
Peripheral Arterial Disease: Improves blood flow to peripheral tissues.