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Flavones: Occurrence, Chemical Nature and Medicinal Benefits

  • Found in parsley, celery, and chamomile.

  • These compounds are known for their anti-inflammatory and antioxidant properties.

  • They may help reduce the risk of heart disease and some cancers.

Occurrence:

  • Flavones are found in various fruits and vegetables, including parsley, celery, and chamomile.

  • They are also present in herbs like thyme and peppermint, and in certain grains.

Chemical Nature:

  • Flavones are a class of flavonoids characterized by a double bond between the second and third carbon atoms in the C ring and a ketone in the fourth position.

  • This structure contributes to their colorless or lightly colored appearance and their antioxidant capacity. Common flavones include apigenin and luteolin.

Medicinal Benefits:

1. Antioxidant Effects:

  • Like other flavonoids, flavones are potent antioxidants, helping to combat oxidative stress and protect against cellular damage.

2. Anti-inflammatory Properties:

  • Flavones can modulate the inflammatory response, potentially beneficial in treating conditions like arthritis and asthma.

3. Cancer Prevention:

  • They may possess anti-cancer properties by inhibiting tumor growth and inducing cell cycle arrest in cancer cells.

4. Cardiovascular Protection:

  • Flavones help in maintaining heart health by improving endothelial function, reducing atherosclerosis, and lowering blood pressure.

5. Neuroprotective:

  • Emerging research suggests that flavones may protect against neurodegenerative diseases through their anti-inflammatory and antioxidant activities.


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