Fluconazole
- BP-S-6-Medicinal Chemistry III
- 3 days ago
- 1 min read
Chemical Structure / Formula of Fluconazole
Formula: C13H12F2N6O
Structure: Triazole antifungal with two fluorine atoms (F) on benzyl ring.
Mechanism of Action
Inhibits lanosterol 14α-demethylase, preventing ergosterol formation.
Uses
Candidiasis (oral, esophageal, vaginal, systemic).
Cryptococcal meningitis (especially in HIV patients).
Dermatophytosis and fungal UTIs.
Side Effects
Hepatotoxicity, GI upset.
QT prolongation, alopecia (long-term use).
