Griseofulvin
- BP-S-6-Medicinal Chemistry III
- Mar 31
- 1 min read
Chemical Structure / Formula of Griseofulvin
Formula: C17H17ClO6
Structure: A benzofuran derivative with a chlorinated ring system.
Mechanism of Action
Binds to fungal microtubules, inhibiting mitosis.
Deposited in keratin-rich tissues (nails, skin, hair), preventing fungal growth.
Uses
Dermatophytic infections (tinea, ringworm, athlete’s foot, onychomycosis).
Side Effects
Hepatotoxicity, GI upset, photosensitivity.
Induces CYP450 (drug interactions).
