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Herbal Disintegrants

  • Disintegrants are substances that help tablets break apart (disintegrate) into smaller particles after administration, facilitating the release and absorption of the active ingredient in the body.

Significance

  1. Drug Bioavailability: Effective disintegration is critical for quick release and hence prompt onset of action.

  2. Efficient Dosage Form: Ensures consistent and reliable performance of solid oral dosage forms.

illustration of Herbal Disintegrants
illustration of Herbal Disintegrants

Examples & Uses

  • Starch (corn, potato, rice): Swells upon contact with water, causing tablet disintegration.

  • Isapghula husk (Plantago ovata): Exhibits excellent swelling properties, promoting rapid disintegration.

  • Agar agar (from seaweeds): Used as a disintegrant due to swelling action.


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