Introduction and classification: Herbal-Drug and Herb-Food Interactions
- S-6-Herbal-Drug-Technology
- Mar 11
- 1 min read
Definition
A drug interaction occurs when a medication, herbal supplement, or food affects the way another substance works in the body, leading to increased, decreased, or harmful effects.
Herb-food interactions refer to the effects of herbal supplements when consumed with certain foods or beverages, which can alter their absorption, metabolism, or elimination.
Classification of Drug Interactions
There are three primary types of drug interactions:
Drug-Drug Interaction
Occurs when two or more drugs interact, altering their safety or effectiveness.
May result from changes in drug metabolism, transport, or receptor activity.
Examples
Warfarin + Aspirin → Increased risk of bleeding.
Ciprofloxacin + Theophylline → Increased toxicity risk.
Drug-Food Interaction
Happens when foods or beverages affect the metabolism, absorption, or transport of drugs.
Can either increase or decrease drug effects, leading to side effects or reduced efficacy.
Examples
Grapefruit juice + Certain medications → Increases drug blood levels, leading to toxicity.
Vitamin K-rich foods + Warfarin → Reduces the anticoagulant effect, increasing clot risk.
Drug-Disease Interaction
Occurs when a medication worsens an existing medical condition.
Can result from changes in drug metabolism, receptor interactions, or side effects.
Examples
Beta-blockers in asthma patients → Worsens breathing difficulties.
NSAIDs in renal impairment → Deteriorates kidney function.
Study of Herbal Drugs: Possible Side Effects and Interactions
