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Introduction to Glycosides

Definition & Structure of Glycosides

  • General Structure: Composed of a sugar (glycone) linked to a non-sugar moiety (aglycone) via a glycosidic bond. (Glycosides)

  • Diversity: The aglycone determines the compound's biological activity and can be phenolic, steroidal, terpenoid, etc.

Biological Functions in Plants

  • Defense & Storage: Store toxic compounds, activated by enzymatic hydrolysis during tissue damage.

  • Regulation: Aid in plant growth, cell signaling, and stress protection.

Pharmacological Applications

  • Drug Prodrugs: Inactive until sugar is removed, enabling controlled release of the aglycone.

  • Therapeutic Uses:

    • Cardiac glycosides improve heart muscle function.

    • Others exhibit laxative, anti-inflammatory, or antimicrobial effects.


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