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Isofluorphate: Chemical Structure, Mechanism of Action, Uses, Side Effects

Chemical Structure:

  • C6H14FO3P

Chemical Structure
Chemical Structure

Mechanism of Action:

Isofluorphate is an organophosphate that irreversibly inhibits acetylcholinesterase, leading to an accumulation of acetylcholine at nerve endings.

Uses:

It was used in the past for the treatment of chronic glaucoma but is not commonly used now due to its long duration of action and potential for toxicity.

Side Effects:

Include prolonged miosis, headache, and typical organophosphate poisoning symptoms such as muscle twitching, respiratory paralysis, and possibly death.

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