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Kanamycin

Chemical Structure / Formula of Kanamycin

  • Formula: C18H36N4O11

  • Similar to neomycin but slightly less toxic.


Chemical Structure of Kanamycin
Chemical Structure of Kanamycin

Mechanism of Action

  • Inhibits 30S ribosomal subunit, leading to bacterial cell death.

Uses

  • Used in tuberculosis (as a second-line drug).

  • Treats severe Gram-negative infections when other antibiotics fail.

  • Topical use for eye and ear infections.

Side Effects

  • Ototoxicity and nephrotoxicity (dose-dependent).

  • Neuromuscular blockade (rare but serious).


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