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Labetalol: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Structure/Formula:

  • C19H24N2O3

Structure of Labetalol
Structure of Labetalol

Mechanism of Action:

  • Labetalol is a mixed alpha and beta-blocker. It blocks beta-1 and beta-2 adrenergic receptors as well as alpha-1 adrenergic receptors, leading to vasodilation and decreased heart rate.

Uses:

  • It is used in the management of hypertension, including hypertension in pregnancy.

Side Effects:

  • Common side effects include fatigue, dizziness, nausea, and in some cases, orthostatic hypotension. It may also cause scalp tingling and may worsen symptoms of asthma.

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