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Levallorphan Tartarate: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Structure:

  • C19H25NO2 · C4H6O6

Chemical Structure
Chemical Structure

Mechanism of Action:

  • Opioid Receptor Antagonist: Levallorphan acts as an antagonist at the mu-opioid receptors and, to a lesser extent, at kappa and delta opioid receptors.

  • Reversal of Opioid Effects: Effective in reversing the effects of opioids, particularly respiratory depression, sedation, and analgesia.

Uses:

  • Opioid Overdose: Used to treat opioid overdose, especially for reversing respiratory depression.

  • Anesthesia: Sometimes used in anesthesia to reverse the effects of opioids used during surgery.

Side Effects:

  • Withdrawal Precipitation: Can cause withdrawal symptoms in opioid-dependent individuals.

  • Nausea and Vomiting: Common side effects.

  • Cardiovascular Changes: Including changes in blood pressure and heart rate.

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