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Levorphanol Tartarate: Chemical Structure, Mechanism of Action, Uses & Side Effects

Chemical Structure:

  • C17H23NO · C4H6O6

Mechanism of Action:

  • A potent opioid agonist with a strong affinity for the mu-opioid receptor. It also has actions at kappa-opioid receptors and NMDA receptors, contributing to its analgesic properties.

Uses:

  • Severe Pain Management: Particularly effective in managing severe and chronic pain conditions.

Side Effects:

  • Respiratory Depression: Significant risk, especially in opioid-naïve patients.

  • CNS Effects: Sedation, dizziness, and mood changes.

  • GI Disturbances: Including nausea and constipation.

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