Structure (Loratadine)
Loratadine is a second-generation antihistamine with a tricyclic structure containing a piperidine ring and an ester linkage.
Chemical Formula: C₂₁H₂₀ClNO₂
Mode of Action
Selective peripheral H₁-receptor antagonist with minimal CNS penetration, thus reducing sedation.
It provides long-lasting antihistaminic effects.
Uses
Allergic Rhinitis: Treats symptoms like sneezing, itching, and runny nose.
Chronic Urticaria: Alleviates hives and skin itching.
Non-Allergic Rhinitis: Effective in treating vasomotor rhinitis.