Mechanism of Solid Mixing
- S-3-Pharmaceutical engineering
- Feb 27
- 1 min read
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Solid mixing involves the following mechanisms:
Convective Mixing
Bulk movement of particles through mechanical means such as blenders, mixers, or tumblers.
Large masses of material are moved from one location to another, promoting mixing.
Diffusive Mixing
Random movement of individual particles within the bulk.
This is akin to the concept of diffusion but at a particulate level, leading to a more uniform distribution over time.
Shear Mixing
Application of shear forces that cause layers of particles to slide over each other.
This is often seen in high-shear mixers and can break agglomerates and improve homogeneity.
Tumbling Mixing
Using rotating drums or V-blenders where gravity causes the particles to tumble and mix as the container rotates.
Solid Mixing Equipment
Ribbon Blenders: Use helical ribbons to move solids within a stationary trough.
Tumble Mixers: Rotate a container to mix particles through tumbling action.
Fluidized Bed Mixers: Use gas or air to suspend and mix particles in a fluid-like state.
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