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Melphalan

Structure

  • Chemical Structure – C13H18Cl2N2O2

Melphalan

Mode of action

  • Through chemical alkylation, melphalan changes the DNA nucleotide guanine and creates connections between DNA strands. This chemical change prevents the creation of RNA and DNA, two processes required for cell survival.

Uses

  • To treat multiple myeloma (a type of cancer of the bone marrow), melphalan is utilised.

  • A particular form of ovarian cancer is also treated with melphalan.


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