Structure
Menadione, also known as vitamin K3, is a synthetic compound with a naphthoquinone structure.
Chemical Formula: C₁₀H₆O₂
Mode of Action
Provitamin K Activity: Serves as a precursor to active vitamin K forms.
Coagulation Factor Synthesis: Supports the carboxylation of glutamate residues on clotting factors II, VII, IX, and X.
Antioxidant Properties: Exhibits free radical scavenging activity.
Uses of Menadione
Vitamin K Deficiency: Treats and prevents bleeding disorders due to inadequate vitamin K.
Warfarin Reversal: Assists in counteracting warfarin-induced anticoagulation.
Antioxidant Supplementation: Employed in research settings for its antioxidant effects.