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Metformin

Structure

  • Metformin Chemical Structure – C₄H₁₁N₅

Metformin

Mode of action

  • Metformin blocks the mitochondrial respiratory chain at the molecular level in the liver, activating AMPK, improving insulin sensitivity and lowering cAMP, which in turn suppresses the production of gluconeogenic enzymes.

Uses

  • Metformin is used to treat type 2 diabetes's high blood sugar levels.


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